Dactinomycin Other names: Actinomycin D Actinomycin C1

Chemical formula: C₆₂H₈₆N₁₂O₁₆  Molecular mass: 1,255.417 g/mol  PubChem compound: 457193

Therapeutic indications

Dactinomycin is indicated for:

Indication

Population group: men, only children (1 year - 12 years old) , adolescents (12 years - 18 years old)

Malignant neoplasm of testis

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Indication

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old)

at least one of
Nephroblastoma
Osteosarcoma of bone
Kaposi's sarcoma
Ewing's sarcoma of bone
Rhabdomyosarcoma
Malignant melanoma of skin

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Indication

Population group: only adults (18 years old or older)

at least one of
Nephroblastoma
Osteosarcoma of bone
Kaposi's sarcoma
Ewing's sarcoma of bone
Rhabdomyosarcoma
Malignant melanoma of skin

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Indication

Population group: women, only adults (18 years old or older)

Malignant neoplasm of placenta

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Indication

Population group: men, only adults (18 years old or older)

Malignant neoplasm of testis

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Dactinomycin is contraindicated in the following cases:

Contraindication

at least one of
Leukopenia
Other primary thrombocytopenia
Secondary thrombocytopenia
Thrombocytopenia, unspecified
Pregnancy

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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