Dapagliflozin

Chemical formula: C₂₁H₂₅ClO₆  Molecular mass: 408.873 g/mol  PubChem compound: 9887712

Therapeutic indications

Dapagliflozin is indicated for:

Diabetes mellitus type 2

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

Dapagliflozin is indicated in adults and children aged 10 years and above for the treatment of insufficiently controlled type 2 diabetes mellitus as an adjunct to diet and exercise:

  • as monotherapy when metformin is considered inappropriate due to intolerance.
  • in addition to other medicinal products for the treatment of type 2 diabetes.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Symptomatic chronic heart failure

Population group: only adults (18 years old or older)

Chronic heart failure

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Chronic kidney disease

Population group: only adults (18 years old or older)

Chronic kidney disease

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Dapagliflozin is contraindicated in the following cases:

Diabetic ketoacidosis

Diabetic ketoacidosis

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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