Dasabuvir

Chemical formula: C₂₆H₂₇N₃O₅S  Molecular mass: 493.58 g/mol  PubChem compound: 56640146

Therapeutic indications

Dasabuvir is indicated for:

Chronic hepatitis C

Population group: only adults (18 years old or older)

Dasabuvir is indicated in combination with other medicinal products for the treatment of chronic hepatitis C (CHC) in adults.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Dasabuvir is contraindicated in the following cases:

Moderate to severe hepatic impairment (Child-Pugh B or C)

at least one of
Hepatic failure stage III
Hepatic failure stage IV

Ethinylestradiol

17 alpha-Ethinylestradiol

Strong CYP2C8 inhibitors

Strong CYP2C8 inhibitors

Apalutamide, enzalutamide, mitotane

at least one of
Apalutamide
Enzalutamide
Mitotane

Carbamazepine

Carbamazepine

Phenobarbital

Phenobarbital

Phenytoin

Phenytoin

Ketoconazole

Ketoconazole

Gemfibrozil

Gemfibrozil

Rifampicin

Rifampicin

Ethinylestradiol

17 alpha-Ethinylestradiol

St. John's Wort (hypericum perforatum)

Hypericum perforatum (St John's Wort)

Lopinavir

Lopinavir

Efavirenz

Efavirenz

Nevirapine, etravirine

at least one of
Nevirapine
Etravirine

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