Delafloxacin

Chemical formula: C₁₈H₁₂ClF₃N₄O₄  Molecular mass: 440.76 g/mol  PubChem compound: 487101

Active ingredient description

Delafloxacin inhibits bacterial topoisomerase IV and DNA gyrase (topoisomerase II), enzymes required for bacterial DNA replication, transcription, repair, and recombination.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
J01MA23 J Antiinfectives for systemic use → J01 Antibacterials for systemic use → J01M Quinolone antibacterials → J01MA Fluoroquinolones
Discover more medicines within J01MA23

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
QUOFENIX Tablet European Medicines Agency (EU) MPI, EU: SmPC
QUOFENIX Powder for concentrate for solution for infusion European Medicines Agency (EU) MPI, EU: SmPC
BAXDELA Tablet / Powder for solution for injection FDA, National Drug Code (US) MPI, US: SPL/PLR

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 189279-58-1
DrugBank Drug: DB11943
PubChem Compound: 487101
RxNorm Ingredient: 1927663
SNOMED-CT Concept: 735011001
Delafloxacin (substance)
UNII Identifier: 6315412YVF
DELAFLOXACIN

Medicines

Delafloxacin is an active ingredient of these brands:

United States (US)

  • BAXDELA as DELAFLOXACIN MEGLUMINE

Austria (AT)

Croatia (HR)

Ecuador (EC)

Estonia (EE)

Finland (FI)

France (FR)

Ireland (IE)

Italy (IT)

Lithuania (LT)

Poland (PL)

Spain (ES)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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