Delapril and Manidipine

Therapeutic indications

Delapril and Manidipine is indicated for:

Essential hypertension

Population group: only adults (18 years old or older)

Delapril/manidipine fixed dose combination is indicated in patients whose blood pressure is not adequately controlled on delapril or manidipine alone.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Delapril and Manidipine is contraindicated in the following cases:

Pregnancy

Pregnancy

Severe hepatic impairment

Hepatic failure stage IV

Severe renal failure

Renal failure stage 5: Kidney failure (GFR <15 mL/min/1.73 m2 or dialysis)

History of angioneurotic oedema associated with previous ACE inhibitor therapy

ACE inhibitor-aggravated angio-oedema

Hereditary or idiopathic angioneurotic oedema

at least one of
Hereditary angioneurotic edema
Idiopathic angio-oedema

Kidney transplantation

Transplant of kidney

Bilateral renal artery stenosis or unilateral renal stenosis in cases of a solitary kidney

RAS - Renal artery stenosis

Hemodynamically relevant aortic and mitral valve stenosis, hypertrophic cardiomyopathy

at least one of
Aortic valve stenosis
Mitral valve stenosis
Hypertrophic cardiomyopathy

Cardiogenic shock

Cardiogenic shock

Primary hyperaldosteronism

Primary hyperaldosteronism

Aliskiren in diabetes mellitus or renal impairment

Aliskiren and additionally at least one of
Diabetes mellitus



Renal failure stage 5: Kidney failure (GFR <15 mL/min/1.73 m2 or dialysis)

Sacubitril/valsartan

Valsartan and sacubitril

Get recommendations

Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

Ask the Reasoner

Related medicines

Summary of Product Characteristics (SPC) : ADAPTUS / DELAMAN Tablet
< Previous: Overview
Next: Precautions >

© All content on this website, including data entry, data processing, decision support tools, "RxReasoner" logo and graphics, is the intellectual property of RxReasoner and is protected by copyright laws. Unauthorized reproduction or distribution of any part of this content without explicit written permission from RxReasoner is strictly prohibited. Any third-party content used on this site is acknowledged and utilized under fair use principles.

⇈