Demeclocycline

Chemical formula: C₂₁H₂₁ClN₂O₈  Molecular mass: 464.853 g/mol  PubChem compound: 54680690

Active ingredient description

Tetracyclines have a broad spectrum of anti-microbial activity and act by interfering with bacterial protein synthesis. They are active against a large number of gram positive and gram negative pathogenic bacteria, including some which are resistant to penicillin.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
D06AA01 Demeclocycline D Dermatologicals → D06 Antibiotics and chemotherapeutics for dermatological use → D06A Antibiotics for topical use → D06AA Tetracycline and derivatives
Discover more medicines within D06AA01
J01AA01 Demeclocycline J Antiinfectives for systemic use → J01 Antibacterials for systemic use → J01A Tetracyclines → J01AA Tetracyclines
Discover more medicines within J01AA01

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
DEMECLOCYCLINE HYDROCHLORIDE Capsules Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
Demeclocycline Hydrochloride 150mg Capsules Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 127-33-3
CAS Substance: 64-73-3
DrugBank Drug: DB00618
KEGG Drug: D00290
PubChem Compound: 54680690
RxNorm Ingredient: 3154
SNOMED-CT Concept: 372779007
Demeclocycline (substance)
UNII Identifier: 5R5W9ICI6O
DEMECLOCYCLINE

Medicines

Demeclocycline is an active ingredient of these brands:

Austria (AT)

  • (combination) LEDERMIX as DEMECLOCYCLINE HYDROCHLORIDE

Estonia (EE)

  • (combination) LEDERMIX as DEMECLOCYCLINE HYDROCHLORIDE

Hong Kong (HK)

  • (combination) LEDERMIX as DEMECLOCYCLINE HYDROCHLORIDE

Ireland (IE)

  • (combination) LEDERMIX as DEMECLOCYCLINE HYDROCHLORIDE

Japan (JP)

Malta (MT)

Netherlands (NL)

Turkey (TR)

  • DEMETIL as DEMECLOCYCLINE HYDROCHLORIDE

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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