Dequalinium

Chemical formula: C₃₀H₄₀N₄²⁺  Molecular mass: 456.665 g/mol  PubChem compound: 2993

Active ingredient description

Dequalinum is an anti-infective and antiseptic agent belonging to the class of quaternary ammonium compounds. The primary mechanism of action is an increase in bacterial cell permeability and the subsequent loss of enzyme activity, finally resulting in cell death.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
D08AH01 Dequalinium D Dermatologicals → D08 Antiseptics and disinfectants → D08A Antiseptics and disinfectants → D08AH Quinoline derivatives
Discover more medicines within D08AH01
G01AC05 Dequalinium G Genito urinary system and sex hormones → G01 Gynecological antiinfectives and antiseptics → G01A ANTIINFECTIVES AND ANTISEPTICS, EXCL. COMBINATIONS WITH CORTICOSTEROIDS → G01AC Quinoline derivatives
Discover more medicines within G01AC05
R02AA02 Dequalinium R Respiratory system → R02 Throat preparations → R02A Throat preparations → R02AA Antiseptics
Discover more medicines within R02AA02

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
FLUOMIZIN Vaginal tablet Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 6707-58-0
DrugBank Drug: DB04209
PubChem Compound: 2993
RxNorm Ingredient: 3226
SNOMED-CT Concept: 395964006
Dequalinium (substance)
UNII Identifier: E7QC7V26B8
DEQUALINIUM

Medicines

Dequalinium is an active ingredient of these brands:

Austria (AT)

Canada (CA)

Croatia (HR)

Ecuador (EC)

Estonia (EE)

  • DONAXYL as DEQUALINIUM CHLORIDE

  • (combination) DECATYLEN as DEQUALINIUM CHLORIDE

Finland (FI)

France (FR)

  • VABLYS as DEQUALINIUM CHLORIDE

Hong Kong (HK)

Lithuania (LT)

  • DONAXYL as DEQUALINIUM CHLORIDE

  • (combination) DECATYLEN as DEQUALINIUM CHLORIDE
  • (combination) EFISOL as DEQUALINIUM CHLORIDE

Nigeria (NG)

Poland (PL)

Romania (RO)

Singapore (SG)

  • (combination) DECATYLEN as DEQUALINIUM CHLORIDE

South Africa (ZA)

Spain (ES)

Turkey (TR)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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