Chemical formula: C₁₆H₁₄O₃ Molecular mass: 254.281 g/mol PubChem compound: 667550
Dexketoprofen belongs to the non-steroidal anti-inflammatory group of drugs. The mechanism of action of Dexketoprofen is related to the reduction of prostaglandin synthesis by the inhibition of cyclooxygenase pathway. Furthermore, the inhibition of the synthesis of prostaglandins could affect other inflammation mediators such as kinins, causing an indirect action which would be additional to the direct action.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| M01AE17 | Dexketoprofen | M Musculo-skeletal system → M01 Antiinflammatory and antirheumatic products → M01A Antiinflammatory and antirheumatic products, non-steroids → M01AE Propionic acid derivatives |
| M02AA27 | M Musculo-skeletal system → M02 Topical products for joint and muscular pain → M02A Topical products for joint and muscular pain → M02AA Antiinflammatory preparations, non-steroids for topical use | |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| KERAL Film-coated tablet | Medicines Authority (MT) | MPI, EU: SmPC | |
| KERAL Solution for injection/infusion | Medicines Authority (MT) | MPI, EU: SmPC |
Dexketoprofen is an active ingredient of these brands:
Austria (AT)Ecuador (EC)
France (FR)Ireland (IE)Lithuania (LT)Mexico (MX)
Netherlands (NL)
Poland (PL)Romania (RO)South Africa (ZA)Spain (ES)Tunisia (TN)
Turkey (TR)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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