Dexmethylphenidate

Chemical formula: C₁₄H₁₉NO₂  Molecular mass: 233.306 g/mol  PubChem compound: 154101

Active ingredient description

Dexmethylphenidate is a CNS stimulant. It is the more pharmacologically active d-enantiomer of racemic methylphenidate. Methylphenidate blocks the reuptake of norepinephrine and dopamine into the presynaptic neuron and increase the release of these monoamines into the extraneuronal space. The mode of therapeutic action in Attention Deficit Hyperactivity Disorder (ADHD) is not known.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
N06BA11 N Nervous system → N06 Psychoanaleptics → N06B Psychostimulants, agents used for ADHD and nootropics → N06BA Centrally acting sympathomimetics
Discover more medicines within N06BA11

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
FOCALIN Tablet FDA, National Drug Code (US) MPI, US: SPL/PLR

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 40431-64-9
DrugBank Drug: DB06701
PubChem Compound: 154101
RxNorm Ingredient: 352372
SNOMED-CT Concept: 767715008
Dexmethylphenidate (substance)
UNII Identifier: M32RH9MFGP
DEXMETHYLPHENIDATE

Medicines

Dexmethylphenidate is an active ingredient of these brands:

United States (US)

  • FOCALIN as DEXMETHYLPHENIDATE HYDROCHLORIDE

Estonia (EE)

  • FOCALIN as DEXMETHYLPHENIDATE HYDROCHLORIDE

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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