Chemical formula: C₈H₇ClN₂O₂S Molecular mass: 230.671 g/mol PubChem compound: 3019
Diazoxide is a peripheral vasodilator and has qualitatively the same effect on blood vessels as benzothiazine compounds, but the effect is more rapid and profound. Unlike benzothiazines, diazoxide is non-diuretic and causes retention of sodium and water. It causes a prompt increase in blood glucose by a direct inhibitory action on the secretion of insulin by the beta cells in the Islets of Langerhans.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| C02DA01 | Diazoxide | C Cardiovascular system → C02 Antihypertensives → C02D Arteriolar smooth muscle, agents acting on → C02DA Thiazide derivatives |
| V03AH01 | Diazoxide | V Various → V03 All other therapeutic products → V03A All other therapeutic products → V03AH Drugs for treatment of hypoglycemia |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| EUDEMINE Sugar coated tablet | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| PROGLYCEM Capsule / Suspension | FDA, National Drug Code (US) | MPI, US: SPL/Old | |
| EUDEMINE Solution for injection | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Diazoxide is an active ingredient of these brands:
United States (US)Brazil (BR)Canada (CA)Estonia (EE)France (FR)Netherlands (NL)United Kingdom (UK)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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