Diclofenac Other names: Diclofenac sodium

Chemical formula: C₁₄H₁₁Cl₂NO₂  Molecular mass: 296.149 g/mol  PubChem compound: 3033

Therapeutic indications

Diclofenac is indicated for:

Ocular pain after radial keratotomy

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

Treatment of ocular pain and discomfort after radial keratotomy.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Inflammation and discomfort after strabismus surgery

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

Treatment of inflammation and discomfort after strabismus surgery.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Pain, inflammation

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

Diclofenac is indicated for relief of all grades of pain and inflammation in a wide range of conditions, including:

  • arthritic conditions: rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, acute gout,
  • acute musculo-skeletal disorders such as periarthritis (for example frozen shoulder), tendinitis, tenosynovitis, bursitis,
  • other painful conditions resulting from trauma, including fracture, low back pain, strains, dislocations, orthopaedic, dental and other minor surgery.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Actinic keratosis

Population group: only adults (18 years old or older)

Diclofenac is indicated for treatment of actinic keratosis (AK).

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Migraine

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

Migraine

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Seasonal allergic conjunctivitis

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

Hay fever conjunctivitis

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Inflammation after argon laser trabeculoplasty (ALT)

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

Control of inflammation after Argon Laser Trabeculoplasty (ALT).

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Post-operative inflammation in cataract surgery

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

Treatment of post-operative inflammation in cataract surgery.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Ocular pain and discomfort associated with corneal epithelial defects

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

Control of ocular pain and discomfort associated with corneal epithelial defects after excimer PRK surgery or accidental non-penetrating trauma.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Post-operative inflammation after eye surgery

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

Control of post-operative inflammation.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Prophylaxis of preoperative miosis

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

Preventive procedure and additionally Miosis

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Diclofenac is contraindicated in the following cases:

History or active or history of gastric or intestinal ulcer, bleeding or perforation

at least one of
Peptic ulcer

Gastrointestinal perforation

Severe hepatic impairment

Hepatic failure stage IV

Non-steroid anti-inflammatory drug-induced angioedema-urticaria

NSAID-induced angio-oedema-urticaria

Aspirin-induced asthma

Aspirin-induced asthma

Severe renal impairment

Renal failure stage 5: Kidney failure (GFR <15 mL/min/1.73 m2 or dialysis)

Severe cardiac impairment

Heart failure New York Heart Assosiation Class IV

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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