Diethylstilbestrol Other names: DES Stilbestrol Stilboestrol

Chemical formula: C₁₈H₂₀O₂  Molecular mass: 268.356 g/mol  PubChem compound: 3054

Active ingredient description

Diethylstilbestrol is a synthetic nonsteroidal estrogen, that was widely used to prevent potential miscarriages by stimulating the synthsis of estrogen and progesterone in the placenta. It was also used for the treatment of symptoms arising during menopause and following ovariectomy and for senile vaginitis and vulvar dystrophy. Diethylstilbestrol was used as a postcoital emergency contraceptive (morning-after pill). It has also been used for the prevention of postpartum breast engorgement, for dysfuctional menstrual cycles and for the treatment of female hypogonadism. Diethylstilbestrol is now rarely used to treat prostate cancer and occacionally in postmenopausal women with breast cancer because of its side-effects.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
G03CB02 Diethylstilbestrol G Genito urinary system and sex hormones → G03 Sex hormones and modulators of the genital system → G03C Estrogens → G03CB Synthetic estrogens, plain
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G03CC05 Diethylstilbestrol G Genito urinary system and sex hormones → G03 Sex hormones and modulators of the genital system → G03C Estrogens → G03CC Estrogens, combinations with other drugs
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L02AA01 Diethylstilbestrol L Antineoplastic and immunomodulating agents → L02 Endocrine therapy → L02A Hormones and related agents → L02AA Estrogens
Discover more medicines within L02AA01

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 56-53-1
DrugBank Drug: DB00255
KEGG Drug: D00577
PubChem Compound: 3054
RxNorm Ingredient: 3390
SNOMED-CT Concept: 396026002
Diethylstilbestrol (substance)
UNII Identifier: 731DCA35BT
DIETHYLSTILBESTROL

Medicines

Diethylstilbestrol is an active ingredient of these brands:

Brazil (BR)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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