Dimeticone is used in many pharmaceutical and cosmetic preparations. A 4% concentration has been found to affect the physico-physiological activity of lice. It is less effective in its ovicidal activity and therefore two applications 7 days apart are required.
The dimeticone solution acts on the lice by a physical process to cover the lice and disrupt the ability of the lice to manage its water balance so that treated insects fail to excrete surplus water. Dimeticone activity is not diminished in insecticide resistant head lice.
Dimeticone is applied topically to the affected area but there is little or no absorption of dimeticone through the skin.
There are no further relevant data.
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