Diosmin

Chemical formula: C₂₈H₃₂O₁₅  Molecular mass: 608.545 g/mol  PubChem compound: 5281613

Active ingredient description

Diosmin (diosmetin 7-O-rutinoside), a flavone derivative also known as venosmine, is a glycoside of diosmetin, which in turn is the 4'-methoxy derivative of luteolin. Diosmin prolongs the vasoconstrictor effect of norepinephrine on the vein wall, increasing venous tone, and therefore reducing venous capacitance, distensibility, and venous stasis. This increases the venous return and reduces venous hyperpressure present in patients suffering from CVI.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
C05CA03 Diosmin C Cardiovascular system → C05 Vasoprotectives → C05C Capillary stabilizing agents → C05CA Bioflavonoids
Discover more medicines within C05CA03

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 520-27-4
DrugBank Drug: DB08995
KEGG Drug: D07858
PubChem Compound: 5281613
RxNorm Ingredient: 3489
SNOMED-CT Concept: 8143001
Diosmin (substance)
UNII Identifier: 7QM776WJ5N
DIOSMIN

Medicines

Diosmin is an active ingredient of these brands:

Austria (AT)

Brazil (BR)

Croatia (HR)

Cyprus (CY)

Ecuador (EC)

Estonia (EE)

France (FR)

Hong Kong (HK)

Lithuania (LT)

Malta (MT)

Mexico (MX)

Nigeria (NG)

Romania (RO)

Singapore (SG)

Spain (ES)

Tunisia (TN)

Turkey (TR)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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