Docetaxel

Chemical formula: C₄₃H₅₃NO₁₄  Molecular mass: 807.879 g/mol  PubChem compound: 148124

Active ingredient description

Docetaxel is an antineoplastic agent which acts by promoting the assembly of tubulin into stable microtubules and inhibits their disassembly which leads to a marked decrease of free tubulin.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
L01CD02 Docetaxel L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01C Plant alkaloids and other natural products → L01CD Taxanes
Discover more medicines within L01CD02

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
DOCETAXEL TEVA Concentrate and solvent for solution European Medicines Agency (EU) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 114977-28-5
DrugBank Drug: DB01248
KEGG Drug: D02165
PubChem Compound: 148124
RxNorm Ingredient: 72962
SNOMED-CT Concept: 386918005
Docetaxel (substance)
UNII Identifier: 15H5577CQD
DOCETAXEL

Medicines

Docetaxel is an active ingredient of these brands:

United States (US)

Austria (AT)

Brazil (BR)

Cyprus (CY)

Ecuador (EC)

Estonia (EE)

France (FR)

Hong Kong (HK)

Ireland (IE)

Japan (JP)

Lithuania (LT)

Mexico (MX)

Netherlands (NL)

Nigeria (NG)

Poland (PL)

Singapore (SG)

South Africa (ZA)

Spain (ES)

Tunisia (TN)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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