Doxorubicin Other names: Doxorubicin hydrochloride

Chemical formula: C₂₇H₂₉NO₁₁  Molecular mass: 543.519 g/mol  PubChem compound: 31703

Therapeutic indications

Doxorubicin is indicated for:

Breast cancer

Population group: only adults (18 years old or older)

Doxorubicin is indicated as monotherapy for patients with metastatic breast cancer, where there is an increased cardiac risk.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Ovarian cancer

Population group: women, only adults (18 years old or older)

Doxorubicin is indicated for treatment of advanced ovarian cancer in women who have failed a first-line platinum-based chemotherapy regimen.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Multiple myeloma

Population group: only adults (18 years old or older)

Doxorubicin is indicated in combination with bortezomib for the treatment of progressive multiple myeloma in patients who have received at least one prior therapy and who have already undergone or are unsuitable for bone marrow transplant.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

AIDS-related Kaposi's sarcoma (KS)

Population group: only adults (18 years old or older)

Doxorubicin is indicated for treatment of AIDS-related Kaposi’s sarcoma (KS) in patients with low CD4 counts (<200 CD4 lymphocytes/mm³) and extensive mucocutaneous or visceral disease.

Doxorubicin may be used as first-line systemic chemotherapy, or as second line chemotherapy in AIDS-KS patients with disease that has progressed with, or in patients intolerant to, prior combination systemic chemotherapy comprising at least two of the following agents: a vinca alkaloid, bleomycin and standard doxorubicin (or other anthracycline).

For this indication, competent medicine agencies globally authorize below treatments (click for details):

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