Doxylamine

Chemical formula: C₁₇H₂₂N₂O  Molecular mass: 270.369 g/mol  PubChem compound: 3162

Active ingredient description

Doxylamine, an ethanolamine, first-generation antihistamine crosses the blood-brain barrier and exerts an antiemetic action by selectively binding to H1 receptors in the brain. Doxylamine is an antihistamine commonly used as a sleep aid. This drug is also used to relieve symptoms of hay fever (allergic rhinitis), hives (rash or itching), and other allergic reactions. Doxylamine is also a potent anticholinergic.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
R06AA09 Doxylamine R Respiratory system → R06 Antihistamines for systemic use → R06A Antihistamines for systemic use → R06AA Aminoalkyl ethers
Discover more medicines within R06AA09

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 469-21-6
DrugBank Drug: DB00366
KEGG Drug: D02327
PubChem Compound: 3162
RxNorm Ingredient: 3642
SNOMED-CT Concept: 44068004
Doxylamine (substance)
UNII Identifier: 95QB77JKPL
DOXYLAMINE

Medicines

Doxylamine is an active ingredient of these brands:

United States (US)

  • (combination) BONJESTA as DOXYLAMINE SUCCINATE
  • (combination) DICLEGIS as DOXYLAMINE SUCCINATE

Austria (AT)

  • HOGGAR as Doxylamine hydrogen succinate
  • (combination) NUPERAL as DOXYLAMINE SUCCINATE
  • (combination) WICK MEDINAIT as DOXYLAMINE SUCCINATE

Brazil (BR)

  • (combination) HYTOS PLUS as DOXYLAMINE SUCCINATE

Canada (CA)

Croatia (HR)

  • HOGGAR as Doxylamine hydrogen succinate

Ecuador (EC)

  • (combination) ASAREL as DOXYLAMINE SUCCINATE
  • (combination) PLENIV as DOXYLAMINE SUCCINATE
  • (combination) PLURIAMIN as DOXYLAMINE SUCCINATE

Estonia (EE)

  • CALMESAN as DOXYLAMINE SUCCINATE
  • (combination) XONVEA as DOXYLAMINE SUCCINATE

Finland (FI)

  • DORMIX as DOXYLAMINE SUCCINATE

France (FR)

  • DONORMYL as DOXYLAMINE SUCCINATE
  • LIDENE as DOXYLAMINE SUCCINATE
  • (combination) CARIBAN as DOXYLAMINE SUCCINATE

Germany (DE)

Hong Kong (HK)

Ireland (IE)

  • (combination) XONVEA as DOXYLAMINE SUCCINATE

Israel (IL)

  • (combination) BONJESTA as DOXYLAMINE SUCCINATE
  • (combination) DICLECTIN as DOXYLAMINE SUCCINATE

Lithuania (LT)

  • DORLAM as DOXYLAMINE SUCCINATE

Malta (MT)

Mexico (MX)

Netherlands (NL)

  • (combination) XONVEA as DOXYLAMINE SUCCINATE

New Zealand (NZ)

  • DOZILE as DOXYLAMINE SUCCINATE
  • (combination) MERSYNDOL as Doxylamine succinate

Nigeria (NG)

  • (combination) MURNISIK as DOXYLAMINE SUCCINATE

Poland (PL)

Singapore (SG)

  • (combination) DICLECTIN as DOXYLAMINE SUCCINATE

South Africa (ZA)

  • DOXYNITE as DOXYLAMINE SUCCINATE
  • REPOSE as DOXYLAMINE SUCCINATE
  • RESTWEL as DOXYLAMINE SUCCINATE
  • SOMNIL as DOXYLAMINE SUCCINATE
  • (combination) ABFLEX-4 as DOXYLAMINE SUCCINATE
  • (combination) ALPHA-DOL as DOXYLAMINE SUCCINATE
  • (combination) ASIC as DOXYLAMINE SUCCINATE
  • (combination) BETAPYN as DOXYLAMINE SUCCINATE
  • (combination) CODOXOL as DOXYLAMINE SUCCINATE
  • (combination) COPA-DOL as DOXYLAMINE SUCCINATE
  • (combination) CYCODACYL as DOXYLAMINE SUCCINATE
  • (combination) DOXSYN as DOXYLAMINE SUCCINATE
  • (combination) DOXY CO as DOXYLAMINE SUCCINATE
  • (combination) FACOCYL as DOXYLAMINE SUCCINATE
  • (combination) LENAPAIN as DOXYLAMINE SUCCINATE
  • (combination) NETHAPRIN as DOXYLAMINE SUCCINATE
  • (combination) NOMOPAIN as DOXYLAMINE SUCCINATE
  • (combination) PARCODOX as DOXYLAMINE SUCCINATE
  • (combination) PAXIDAL as DOXYLAMINE SUCCINATE
  • (combination) PHARMADOL as DOXYLAMINE SUCCINATE
  • (combination) PYNSTOP as DOXYLAMINE SUCCINATE
  • (combination) RESDOL as DOXYLAMINE SUCCINATE
  • (combination) SEDAPAIN as DOXYLAMINE SUCCINATE
  • (combination) SEDINOL as DOXYLAMINE SUCCINATE
  • (combination) SYNDOL as DOXYLAMINE SUCCINATE
  • (combination) TENSOPYN as DOXYLAMINE SUCCINATE
  • (combination) VICKS MEDINITE as DOXYLAMINE SUCCINATE

Spain (ES)

Turkey (TR)

  • DORMIR as DOXYLAMINE SUCCINATE
  • (combination) PRIFEMYN as DOXYLAMINE SUCCINATE
  • (combination) PRILAM as DOXYLAMINE SUCCINATE

United Kingdom (UK)

  • (combination) XONVEA as DOXYLAMINE SUCCINATE

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

 
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