Chemical formula: C₃₁H₄₄N₂O₅S Molecular mass: 556.756 g/mol PubChem compound: 208898
Dronedarone is a multichannel blocker inhibiting the potassium currents (including IK(Ach), IKur, IKr, IKs) and thus prolonging cardiac action potential and refractory periods (Class III). It also inhibits the sodium currents (Class Ib) and the calcium currents (Class IV). It non-competitively antagonises adrenergic activities (Class II).
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| C01BD07 | Dronedarone | C Cardiovascular system → C01 Cardiac therapy → C01B Antiarrhythmics, class I and III → C01BD Antiarrhythmics, class III |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| MULTAQ Film-coated tablet | European Medicines Agency (EU) | MPI, EU: SmPC |
Dronedarone is an active ingredient of these brands:
United States (US)
Austria (AT)
Canada (CA)
Cyprus (CY)
Estonia (EE)
Finland (FI)
France (FR)
Hong Kong (HK)
Ireland (IE)
Italy (IT)
Lithuania (LT)
Mexico (MX)
Poland (PL)
Singapore (SG)
Spain (ES)
United Kingdom (UK)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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