Droperidol

Chemical formula: C₂₂H₂₂FN₃O₂  Molecular mass: 379.427 g/mol  PubChem compound: 3168

Therapeutic indications

Droperidol is indicated for:

Prevention and treatment of post-operative nausea and vomiting (PONV)

Population group: only elderly (65 years old or older)

at least one of
Postoperative nausea and vomiting
Preventive procedure and additionally Postoperative nausea and vomiting

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Prevention and treatment of post-operative nausea and vomiting (PONV)

Population group: only adults (18 - 65 years old)

at least one of
Postoperative nausea and vomiting
Preventive procedure and additionally Postoperative nausea and vomiting

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Prevention and treatment of post-operative nausea and vomiting (PONV)

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old)

at least one of
Postoperative nausea and vomiting
Preventive procedure and additionally Postoperative nausea and vomiting

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Prevention of nausea and vomiting induced by morphine derivatives

Population group: only adults (18 - 65 years old)

Prevention of nausea and vomiting induced by morphine derivatives during post-operative patient controlled analgesia (PCA)

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Droperidol is contraindicated in the following cases:

Hypersensitivity to droperidol

Droperidol allergy

Severe depression

Severe depression

Parkinson's disease

Parkinson's disease

Comatose states

Coma

Phaeochromocytoma

Phaeochromocytoma

Bradycardia, drugs leading to bradycardia

at least one of
Bradycardia
Drug-induced bradycardia

Hypokalaemia, hypomagnesemia

at least one of
Hypokalemia
Hypomagnesaemia

Prolonged QT interval, medicinal products that prolong the QT interval

at least one of
Prolonged QT interval
Long QT syndrome
Drugs prolonging QT interval
Drugs inducing Torsade de Pointes

Hypersensitivity to butyrophenones

Butyrophenone allergy

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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Summary of Product Characteristics (SPC) 2018: XOMOLIX Solution for injection
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