Chemical formula: C₁₀H₁₆NO+ Molecular mass: 166.24 g/mol PubChem compound: 3202
Edrophonium is an antagonist to cholinesterase, the enzyme which normally destroys acetylcholine. The action of edrophonium can briefly be described, therefore, as the potentiation of naturally occurring acetylcholine. It differs from neostigmine and pyridostigmine in the rapidity and brevity of its action.
Following intravenous injection of edrophonium an initial rapid phase of elimination (0.5-2 minutes) precedes a much slower decline (24-45 minutes). It is suggested that the rapid fall in plasma concentration of edrophonium is not primarily due to metabolism and excretion but to the rapid uptake of the drug by other tissues.
No further data.
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