Chemical formula: C₁₄H₉ClF₃NO₂ Molecular mass: 315.675 g/mol PubChem compound: 64139
Efavirenz is a NNRTI of HIV-1. Efavirenz is a non-competitive inhibitor of HIV-1 reverse transcriptase (RT) and does not significantly inhibit HIV-2 RT or cellular DNA polymerases (α, β, γ or δ).
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
ATC code | Group title | Classification |
---|---|---|
J05AG03 | Efavirenz | J Antiinfectives for systemic use → J05 Antivirals for systemic use → J05A Direct acting antivirals → J05AG Non-nucleoside reverse transcriptase inhibitors |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
Title | Information Source | Document Type | |
---|---|---|---|
STOCRIN Film-coated tablet | European Medicines Agency (EU) | MPI, EU: SmPC |
Efavirenz is an active ingredient of these brands:
Australia (AU)Brazil (BR)Croatia (HR)
Ecuador (EC)
Finland (FI)
Israel (IL)Japan (JP)Mexico (MX)New Zealand (NZ)Nigeria (NG)Singapore (SG)South Africa (ZA)
Tunisia (TN)Turkey (TR)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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