Enoxaparin Other names: Enoxaparin sodium

Therapeutic indications

Enoxaparin is indicated for:

Prophylaxis of venous thromboembolic disease in orthopaedic, general, cancer surgery

Population group: only adults (18 years old or older)

Prophylaxis of venous thromboembolic disease in moderate and high risk surgical patients, in particular those undergoing orthopaedic or general surgery including cancer surgery.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Prophylaxis of venous thromboembolic disease in acute heart failure, respiratory insufficiency, infections, rheumatic diseases

Population group: only adults (18 years old or older)

Prophylaxis of venous thromboembolic disease in medical patients with an acute illness (such as acute heart failure, respiratory insufficiency, severe infections or rheumatic diseases) and reduced mobility at increased risk of venous thromboembolism.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Deep vein thrombosis (DVT), pulmonary embolism (PE)

Population group: only adults (18 years old or older)

Treatment of deep vein thrombosis (DVT) and pulmonary embolism (PE), excluding PE likely to require thrombolytic therapy or surgery.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Prevention of thrombus formation in haemodialysis

Population group: only adults (18 years old or older)

Prevention of thrombus formation in extra corporeal circulation during haemodialysis.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Acute coronary syndrome

Population group: only adults (18 - 65 years old)

Acute coronary syndrome:

  • Treatment of unstable angina and Non ST-segment elevation myocardial infarction (NSTEMI), in combination with oral acetylsalicylic acid.
  • Treatment of acute ST-segment elevation myocardial infarction (STEMI) including patients to be managed medically or with subsequent percutaneous coronary intervention (PCI).

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Acute coronary syndrome

Population group: only elderly (65 years old or older)

Acute coronary syndrome:

  • Treatment of unstable angina and Non ST-segment elevation myocardial infarction (NSTEMI), in combination with oral acetylsalicylic acid.
  • Treatment of acute ST-segment elevation myocardial infarction (STEMI) including patients to be managed medically or with subsequent percutaneous coronary intervention (PCI).

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Enoxaparin is contraindicated in the following cases:

Bleeding

Bleeding

Hypersensitivity to enoxaparin

Enoxaparin allergy

Immune mediated heparin-induced thrombocytopenia (HIT), heparin antibodies

at least one of
Heparin-induced thrombocytopenia
Heparin antibody

Spinal anaesthesia, epidural anaesthesia, loco-regional anaesthesia

at least one of
Spinal block
Epidural anesthesia
Regional anesthesia

Haemorrhagic stroke, gastrointestinal ulcer, brain surgery, spinal surgery, ophthalmic surgery, oesophageal varices

at least one of
Cerebral hemorrhage
Gastrointestinal ulcer
Procedure on brain
Procedure on spine
Surgical procedure on eye region
Esophageal varices
Congenital arteriovenous malformation
Arteriovenous malformation of stomach
Arteriovenous malformation of kidney
Dural arteriovenous malformation
Aneurysm
Congenital vascular disorder

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