Esmolol Other names: Esmolol hydrochloride

Chemical formula: C₁₆H₂₅NO₄  Molecular mass: 295.374 g/mol  PubChem compound: 59768

Therapeutic indications

Esmolol is indicated for:

Supraventricular tachycardia

Population group: only adults (18 years old or older)

Esmolol is indicated for supraventricular tachycardia (except for pre- excitation syndromes), and for the rapid control of ventricular rate in patients with atrial fibrillation or atrial flutter in perioperative, postoperative, or other circumstances where short-term control of the ventricular rate with a short acting agent is desirable.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Perioperative tachycardia and hypertension

Population group: only adults (18 years old or older)

Esmolol is also indicated for tachycardia and hypertension occurring in the perioperative phase and non-compensatory sinus tachycardia where, in physician’s judgement the rapid heart rate requires specific intervention.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Esmolol is contraindicated in the following cases:

Severe sinus bradycardia, "Sick sinus"-syndrome

at least one of
Severe sinus bradycardia
Sick sinus syndrome

2nd degree AV-block, 3rd degree AV-block

at least one of
Second degree atrioventricular block
Complete atrioventricular block

Cardiogenic shock, decompensated heart failure

at least one of
Cardiogenic shock
Decompensated chronic heart failure

Severe hypotension

Hypotension

Non-treated phaeochromocytoma

Phaeochromocytoma

Pulmonary hypertension

Pulmonary hypertension

Acute asthma

Exacerbation of asthma

Metabolic acidosis

Metabolic acidosis

Verapamil

Verapamil

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Summary of Product Characteristics (SPC) 2018: ESMOLOL HYDROCHLORIDE Powder for concentrate solution
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