Estramustine Other names: Estramustine phosphate ΕΜΡ

Chemical formula: C₂₃H₃₁Cl₂NO₃  Molecular mass: 440.403 g/mol  PubChem compound: 259331

Therapeutic indications

Estramustine is indicated for:

Carcinoma of the prostate

Population group: men, only adults (18 years old or older)

Carcinoma of the prostate, especially in cases unresponsive to, or relapsing after, treatment by conventional oestrogens (stilboestrol, polyoestradiol phosphate etc.) or by orchidectomy.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Estramustine is contraindicated in the following cases:

Peptic ulceration

Peptic ulcer

Active thrombosis, thromboembolic disorders

at least one of
Thrombosis
Thromboembolic disorder

Fluid retention

Body fluid retention

Severe liver dysfunction

Hepatic failure stage IV

Myocardial insufficiency

Myocardial dysfunction

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Summary of Product Characteristics (SPC) 2019: ESTRACYT Capsule
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