The active ingredients of conjugated estrogens are primarily the sulfate esters of estrone, equilin sulfates, 17α-estradiol and 17β-estradiol. These substitute for the loss of estrogen production in menopausal women, and alleviate menopausal symptoms. Estrogens prevent bone loss following menopause or ovariectomy.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| G03CA57 | Conjugated estrogens | G Genito urinary system and sex hormones → G03 Sex hormones and modulators of the genital system → G03C Estrogens → G03CA Natural and semisynthetic estrogens, plain |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| PREMARIN Coated tablet | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| PREMARIN Film-coated tablet | FDA, National Drug Code (US) | MPI, US: SPL/PLR | |
| PREMARIN Vaginal cream | FDA, National Drug Code (US) | MPI, US: SPL/PLR | |
| PREMARIN Powder for solution for injection | FDA, National Drug Code (US) | MPI, US: SPL/Old |
Estrogens, conjugated is an active ingredient of these brands:
Austria (AT)
Croatia (HR)
Finland (FI)
France (FR)
Israel (IL)
Japan (JP)Lithuania (LT)
Netherlands (NL)
Nigeria (NG)Poland (PL)
Singapore (SG)South Africa (ZA)
Spain (ES)
Turkey (TR)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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