Chemical formula: C₁₈H₂₂O₂ Molecular mass: 270.366 g/mol PubChem compound: 5870
Estrone is an aromatized C18 steroid with a 3-hydroxyl group and a 17-ketone. Estrone is a major mammalian estrogen. It is converted from androstenedione directly, or from testosterone via estradiol. It is produced primarily in the ovaries, placenta, and in peripheral tissues (especially adipose tissue) through conversion of adrostenedione.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| G03CA07 | Estrone | G Genito urinary system and sex hormones → G03 Sex hormones and modulators of the genital system → G03C Estrogens → G03CA Natural and semisynthetic estrogens, plain |
| G03CC04 | Estrone | G Genito urinary system and sex hormones → G03 Sex hormones and modulators of the genital system → G03C Estrogens → G03CC Estrogens, combinations with other drugs |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| ESTRAGYN Vaginal cream | Health Products and Food Branch (CA) | MPI, CA: SPM |
Estrone is an active ingredient of these brands:
Canada (CA)Turkey (TR)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
© All content on this website, including data entry, data processing, decision support tools, "RxReasoner" logo and graphics, is the intellectual property of RxReasoner and is protected by copyright laws. Unauthorized reproduction or distribution of any part of this content without explicit written permission from RxReasoner is strictly prohibited. Any third-party content used on this site is acknowledged and utilized under fair use principles.
