Aethosuximide Other names: Ethosuccimide Ethosuxide Ethosuccinimide Etosuximida Ethosuximide

Chemical formula: C₇H₁₁NO₂  Molecular mass: 141.168 g/mol  PubChem compound: 3291

Active ingredient description

Ethosuximide is an anti-epileptic of the class of succinimides that apparently exerts multiple mechanisms of action. The activity of ethosuximide in absence type epilepsy seems to rely primarily on the inhibition of T-type calcium channels in the thalamus.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
N03AD01 Ethosuximide N Nervous system → N03 Antiepileptics → N03A Antiepileptics → N03AD Succinimide derivatives
Discover more medicines within N03AD01

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
ETHOSUXIMIDE NEURAXPHARMA Oral solution Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 77-67-8
DrugBank Drug: DB00593
KEGG Drug: D00539
PubChem Compound: 3291
RxNorm Ingredient: 4135
SNOMED-CT Concept: 322899006
Ethosuximide (substance)
SNOMED-CT Concept: 387244008
Ethosuximide (substance)
UNII Identifier: 5SEH9X1D1D
ETHOSUXIMIDE

Medicines

Aethosuximide is an active ingredient of these brands:

United States (US)

Australia (AU)

Austria (AT)

Brazil (BR)

Canada (CA)

Estonia (EE)

France (FR)

Ireland (IE)

Japan (JP)

Lithuania (LT)

Malta (MT)

Mexico (MX)

Netherlands (NL)

New Zealand (NZ)

Poland (PL)

Romania (RO)

Turkey (TR)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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