Chemical formula: C₂₂H₂₈O₂ Molecular mass: 324.457 g/mol PubChem compound: 6917715
Etonogestrel is the biologically active metabolite of desogestrel, a progestagen widely used in OCs. It is structurally derived from 19-nortestosterone and binds with high affinity to progesterone receptors in the target organs. The contraceptive effect of etonogestrel is primarily achieved by inhibition of ovulation.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| G03AC08 | Etonogestrel | G Genito urinary system and sex hormones → G03 Sex hormones and modulators of the genital system → G03A Hormonal contraceptives for systemic use → G03AC Progestogens |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| NEXPLANON Implant | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Etonogestrel is an active ingredient of these brands:
Australia (AU)Austria (AT)Croatia (HR)
Estonia (EE)Finland (FI)Ireland (IE)
Israel (IL)
Lithuania (LT)New Zealand (NZ)Poland (PL)
Singapore (SG)Spain (ES)United Kingdom (UK)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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