Felbinac Other names: Biphenylylacetic acid

Chemical formula: C₁₄H₁₂O₂  Molecular mass: 212.244 g/mol  PubChem compound: 3332

Pharmacodynamic properties

Felbinac is an anti-inflammatory/analgesic agent which has been developed into a topical gel for local treatment of pain and inflammation associated with conditions of the musculo-skeletal system.

Pharmacokinetic properties

This medicine administered in a pharmacokinetic study achieves similar low circulating levels of felbinac to this medicine.

Preclinical safety data

Testing of biphenylacetic acid includes single and repeat dose studies, foetal toxicity and fertility studies, mutagenic and carcinogenic potential studies which show an acceptable toxicity profile for the active ingredient.

A primary dermal irritation study has shown this medicine to be non-irritant and that it can be safely applied to human skin.

This medicine is irritant to the eye but the irritation subsides within 7 days.

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