Fentanyl Other names: Fentanil Fentanyl citrate Phentanyl

Chemical formula: C₂₂H₂₈N₂O  Molecular mass: 336.471 g/mol  PubChem compound: 3345

Therapeutic indications

Fentanyl is indicated for:

Severe chronic pain

Population group: only adults (18 years old or older)

Fentanyl is indicated for management of severe chronic pain that requires continuous long term opioid administration.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Severe chronic pain

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old)

Long term management of severe chronic pain in children from 2 years of age who are receiving opioid therapy.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Breakthrough pain (BTP)

Population group: only adults (18 years old or older)

Fentanyl is indicated for the management of breakthrough pain (BTP) in adults who are already receiving maintenance opioid therapy for chronic cancer pain. Breakthrough pain is a transitory exacerbation of pain that occurs on a background of otherwise controlled persistent pain.

Patients receiving maintenance opioid therapy are those who are taking at least 60 mg of oral morphine daily, at least 25 micrograms of transdermal fentanyl per hour, at least 30 mg of oxycodone daily, at least 8 mg of oral hydromorphone daily or an equianalgesic dose of another opioid for a week or longer.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Neuroleptanalgesia during surgical procedures, severe pain

Population group: only adults (18 years old or older)

Fentanyl citrate is a narcotic analgesic. In low doses it is used to provide analgesia during short surgical procedures and as a premedicant. In higher doses it is employed as an analgesic/respiratory depressant in patients who need assisted ventilation. In combination with a neuroleptic drug, fentanyl is employed as part of the technique of neuroleptanalgesia. Fentanyl is also used in the treatment of severe pain, such as that of myocardial infarction.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Neuroleptanalgesia during surgical procedures, severe pain

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old)

Fentanyl citrate is a narcotic analgesic. In low doses it is used to provide analgesia during short surgical procedures and as a premedicant. In higher doses it is employed as an analgesic/respiratory depressant in patients who need assisted ventilation. In combination with a neuroleptic drug, fentanyl is employed as part of the technique of neuroleptanalgesia. Fentanyl is also used in the treatment of severe pain, such as that of myocardial infarction.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Fentanyl is contraindicated in the following cases:

Severe respiratory depression

Decreased respiratory function

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