Flumazenil Other names: Flumazepil

Chemical formula: C₁₅H₁₄FN₃O₃  Molecular mass: 303.288 g/mol  PubChem compound: 3373

Active ingredient description

Flumazenil, an imidazobenzodiazepine, is a benzodiazepine antagonist which, by competitive interaction, blocks the effects of substances acting via the benzodiazepine-receptor. Neutralisation of paradoxal reactions of benzodiazepines has been reported.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
V03AB25 Flumazenil V Various → V03 All other therapeutic products → V03A All other therapeutic products → V03AB Antidotes
Discover more medicines within V03AB25

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
FLUMAZENIL Solution for injection or infusion Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

3D molecular structure

3D representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 78755-81-4
DrugBank Drug: DB01205
KEGG Drug: D00697
PubChem Compound: 3373
RxNorm Ingredient: 4457
SNOMED-CT Concept: 387575000
Flumazenil (substance)
UNII Identifier: 40P7XK9392
FLUMAZENIL

Medicines

Flumazenil is an active ingredient of these brands:

Austria (AT)

Croatia (HR)

Ecuador (EC)

Estonia (EE)

Hong Kong (HK)

Ireland (IE)

Japan (JP)

Lithuania (LT)

Netherlands (NL)

New Zealand (NZ)

Romania (RO)

Singapore (SG)

Spain (ES)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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