Fluocinolone Other names: Fluocinolone acetonide

Chemical formula: C₂₄H₃₀F₂O₆  Molecular mass: 452.488 g/mol  PubChem compound: 6215

Active ingredient description

Fluocinolone acetonide is a synthetic fluorinated corticosteroid with anti-inflammatory, antipruritic, and vasoconstrictive properties.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
C05AA10 Fluocinolone acetonide C Cardiovascular system → C05 Vasoprotectives → C05A Agents for treatment of hemorrhoids and anal fissures for topical use → C05AA Corticosteroids
Discover more medicines within C05AA10
D07AC04 Fluocinolone acetonide D Dermatologicals → D07 Corticosteroids, dermatological preparations → D07A Corticosteroids, plain → D07AC Corticosteroids, potent (group III)
Discover more medicines within D07AC04
S01BA15 Fluocinolone acetonide S Sensory organs → S01 Ophthalmologicals → S01B Antiinflammatory agents → S01BA Corticosteroids, plain
Discover more medicines within S01BA15
S02BA08 S Sensory organs → S02 Otologicals → S02B Corticosteroids → S02BA Corticosteroids
Discover more medicines within S02BA08

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
DERMOTIC Ear drops FDA, National Drug Code (US) MPI, US: SPL/Old
ILUVIEN Intravitreal implant Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
RETISERT Implant FDA, National Drug Code (US) MPI, US: SPL/PLR

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 67-73-2
DrugBank Drug: DB00591
KEGG Drug: D01825
PubChem Compound: 6215
RxNorm Ingredient: 4461
SNOMED-CT Concept: 331918005
Fluocinolone acetonide (substance)
SNOMED-CT Concept: 396059004
Fluocinolone acetonide (substance)
UNII Identifier: 0CD5FD6S2M
FLUOCINOLONE ACETONIDE

Medicines

Fluocinolone is an active ingredient of these brands:

United States (US)

Austria (AT)

Brazil (BR)

Canada (CA)

Cyprus (CY)

Ecuador (EC)

Estonia (EE)

Finland (FI)

France (FR)

Germany (DE)

Hong Kong (HK)

Ireland (IE)

Japan (JP)

Lithuania (LT)

Malta (MT)

Mexico (MX)

Netherlands (NL)

New Zealand (NZ)

Poland (PL)

Romania (RO)

Singapore (SG)

South Africa (ZA)

Spain (ES)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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