Flurbiprofen

Chemical formula: C₁₅H₁₃FO₂  Molecular mass: 244.261 g/mol  PubChem compound: 3394

Therapeutic indications

Flurbiprofen is indicated for:

Inhibition of intraoperative miosis, post-operative trabeculoplasty inflammation in the anterior segment of the eye

Population group: only adults (18 years old or older)

Flurbiprofen is indicated for:

  • the inhibition of intraoperative miosis. Flurbiprofen does not have intrinsic mydriatic properties and does not replace mydriatic agents.
  • the management of post-operative and post-laser trabeculoplasty inflammation in the anterior segment of the eye in patients in whom steroid therapy is not recommended.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Rheumatoid disease, osteoarthritis, ankylosing spondylitis, musculoskeletal disorders, periarthritis, frozen shoulder, bursitis

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

For the treatment of rheumatoid disease, osteoarthritis, ankylosing spondylitis, musculoskeletal disorders and trauma such as periarthritis, frozen shoulder, bursitis, tendinitis, tenosynovitis, low back pain, sprains and strains.

Flurbiprofen is also indicated for its analgesic effect in the relief of mild to moderate pain in conditions such as dental pain, post-operative pain, dysmenorrhoea and migraine.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Dysmenorrhoea

Population group: only adolescents (12 years - 18 years old) , adults (18 - 65 years old)

Period pain

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Sore throat

Population group: only adults (18 - 65 years old)

Short term symptomatic relief of sore throat.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Flurbiprofen is contraindicated in the following cases:

History of hypersensitivity reactions to NSAIDs

Non-steroidal anti-inflammatory drug allergy

Severe heart failure, severe hepatic failure, severe renal failure

at least one of
Heart failure
New York Heart Association Classification - Class IV

Renal failure stage 5: Kidney failure (GFR <15 mL/min/1.73 m2 or dialysis)
Hepatic failure stage IV

Pregnancy

Pregnancy

Gastrointestinal bleeding, gastrointestinal perforation

at least one of
Gastrointestinal hemorrhage
Gastrointestinal perforation
History of gastrointestinal bleed

Ulcerative colitis, Crohn's disease, recurrent peptic ulceration, gastrointestinal haemorrhage

at least one of
Colitis gravis
H/O: ulcerative colitis
Crohn's disease
Peptic ulcer
Gastrointestinal hemorrhage
Disorder of hematopoietic structure

Epithelial herpes simplex keratitis

at least one of
Herpes simplex virus epithelial keratitis
Herpes simplex dendritic keratitis

Surgical procedure on eye region

Surgical procedure on eye region

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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