Chemical formula: C₁₁H₁₁F₃N₂O₃ Molecular mass: 276.212 g/mol PubChem compound: 3397
Flutamide is a non-steroidal, highly specific, orally active anti-androgenic agent. The pharmacologically active metabolite, hydroxyflutamide, is believed to exert an anti-androgenic effect directly on the target tissues, either by inhibiting androgen uptake or by blocking cytoplasmic and nuclear binding of androgen. Flutamide is indicated for the treatment of advanced prostatic carcinoma in which suppression of testosterone effects is indicated.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| L02BB01 | Flutamide | L Antineoplastic and immunomodulating agents → L02 Endocrine therapy → L02B Hormone antagonists and related agents → L02BB Anti-androgens |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| FLUTAMIDE Tablet | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| FLUTAN Tablet | Υπουργείο Υγείας (CY) | MPI, EU: SmPC |
Flutamide is an active ingredient of these brands:
Australia (AU)Brazil (BR)Cyprus (CY)Finland (FI)Hong Kong (HK)Japan (JP)Malta (MT)New Zealand (NZ)Nigeria (NG)Romania (RO)South Africa (ZA)Spain (ES)Turkey (TR)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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