Follitropin alfa Other names: FSH Follicle-stimulating hormone

Therapeutic indications

Follitropin alfa is indicated for:

Anovulation

Population group: women, only adults (18 - 65 years old)

Anovulation (including polycystic ovarian syndrome) in women who have been unresponsive to treatment with clomifene citrate.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Stimulation of multifollicular development

Population group: women, only adults (18 - 65 years old)

Stimulation of multifollicular development in women undergoing superovulation for assisted reproductive technologies (ART) such as in vitro fertilisation (IVF), gamete intra-fallopian transfer and zygote intra-fallopian transfer.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Hypogonadotropic hypogonadism

Population group: women, only adults (18 - 65 years old)

Follitropin alfa in association with a luteinising hormone (LH) preparation is recommended for the stimulation of follicular development in women with severe LH and FSH deficiency. In clinical trials these patients were defined by an endogenous serum LH level<1.2 IU/L.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Hypogonadotropic hypogonadism

Population group: men, only adults (18 - 65 years old)

Follitropin alfa is indicated for the stimulation of spermatogenesis in men who have congenital or acquired hypogonadotropic hypogonadism with concomitant human chorionic gonadotropin (hCG) therapy.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Follitropin alfa is contraindicated in the following cases:

Tumours of the hypothalamus or pituitary gland

Tumor of hypothalamus

Ovarian enlargement

Ovarian enlargement

Ovarian cyst not due to polycystic ovarian syndrome

Ovarian cyst and additionally not Polycystic ovary

Gynaecological haemorrhages of unknown aetiology

at least one of
Hematoma of vulva
Hemorrhagic oviduct
Hematoma of uterus
Hemorrhage of cervix

Mammary carcinoma

CA - Carcinoma of breast

Ovarian carcinoma

Malignant epithelial tumor of ovary

Uterine carcinoma

Carcinoma of uterus

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