Chemical formula: C₂₃H₃₈O₅ Molecular mass: 394.552 g/mol PubChem compound: 5282237
Gemeprost (16, 16-dimethyl-trans-delta2 PGE1 methyl ester) is a prostaglandin E1 analogue. Both in pregnant and non-pregnant animals, it causes contraction of the uterus and causes softening and decreases resistance of cervical tissue. Gemeprost depresses placental and uterine blood flow but those actions are secondary to the main uterine stimulation.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| G02AD03 | Gemeprost | G Genito urinary system and sex hormones → G02 Other gynecologicals → G02A Oxytocics → G02AD Prostaglandins |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| CERVAGEM Vaginal pessary | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Gemeprost is an active ingredient of these brands:
France (FR)Japan (JP)Singapore (SG)United Kingdom (UK)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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