Givinostat

Chemical formula: C₂₄H₂₇N₃O₄  Molecular mass: 421.2 g/mol  PubChem compound: 9804992

Active ingredient description

Givinostat is a histone deacetylase inhibitor. The precise mechanism by which givinostat exerts its effect in patients with Duchenne muscular dystrophy (DMD) is unknown.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
M09AX14 M Musculo-skeletal system → M09 Other drugs for disorders of the musculo-skeletal system → M09A Other drugs for disorders of the musculo-skeletal system → M09AX Other drugs for disorders of the musculo-skeletal system
Discover more medicines within M09AX14

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
DUVYZAT Oral suspension FDA, National Drug Code (US) MPI, US: SPL/PLR

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 497833-27-9
DrugBank Drug: DB12645
KEGG Drug: D12742
PubChem Compound: 9804992
UNII Identifier: 5P60F84FBH
GIVINOSTAT

Medicines

Givinostat is an active ingredient of these brands:

United States (US)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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