Chemical formula: C₃H₈O₃ Molecular mass: 92.094 g/mol PubChem compound: 753
When taken by mouth, glycerin has demulcent properties.
Externally, glycerin has humectant emollient properties.
Glycerol by the rectal route promotes peristalsis and evacuation of the lower bowel by virtue of its irritant action.
Glycerin is readily absorbed from the gastrointestinal tract and peak serum concentrations occur within 60-90 minutes. Following absorption, glycerin is distributed throughout the blood. It is metabolised to carbon dioxide and glycogen and is used in the synthesis of body fats principally in the liver. The elimination half life of glycerin is about 30-45 minutes.
No information has been found on the pharmacokinetics of glycerol administered rectally.
No data of relevance, which is additional to that included on other sections of the summary.
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