Guanabenz

Chemical formula: C₈H₈Cl₂N₄  Molecular mass: 230.013 g/mol  PubChem compound: 5702063

Active ingredient description

Guanabenz is an orally active central alpha-2 adrenergic agonist. Its antihypertensive action appears to be mediated via stimulation of central alpha adrenergic receptors, resulting in a decrease of sympathetic outflow from the brain at the bulbar level to the peripheral circulatory system.

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
WYTENSIN Tablet Web Search MPI, Generic

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 5051-62-7
DrugBank Drug: DB00629
KEGG Drug: D04375
PubChem Compound: 5702063
RxNorm Ingredient: 5033
SNOMED-CT Concept: 372867002
Guanabenz (substance)
UNII Identifier: GGD30112WC
GUANABENZ

Medicines

Guanabenz is an active ingredient of these brands:

Japan (JP)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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