Chemical formula: C₉H₉Cl₂N₃O Molecular mass: 246.093 g/mol PubChem compound: 3519
Guanfacine is a selective alpha2A-adrenergic receptor agonist in that it has 15-20 times higher affinity for this receptor subtype than for the alpha2B or alpha2C subtypes. Guanfacine is a non-stimulant. The mode of action of guanfacine in ADHD is not fully established.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| C02AC02 | Guanfacine | C Cardiovascular system → C02 Antihypertensives → C02A Antiadrenergic agents, centrally acting → C02AC Imidazoline receptor agonists |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| INTUNIV Prolonged-release tablet | European Medicines Agency (EU) | MPI, EU: SmPC |
Guanfacine is an active ingredient of these brands:
United States (US)
Australia (AU)
Austria (AT)
Canada (CA)
Croatia (HR)
Estonia (EE)
Finland (FI)
France (FR)
Ireland (IE)
Japan (JP)
Lithuania (LT)
Netherlands (NL)
Poland (PL)
Spain (ES)
United Kingdom (UK)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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