Histamine

Chemical formula: C₅H₉N₃  Molecular mass: 111.145 g/mol  PubChem compound: 774

Therapeutic indications

Histamine is indicated for:

Acute myeloid leukaemia (AML) in first remission concomitantly treated with interleukin-2 (IL-2)

Population group: only adults (18 - 65 years old)

Histamine maintenance therapy is indicated for adult patients with acute myeloid leukaemia (AML) in first remission concomitantly treated with interleukin-2 (IL-2). The efficacy of histamine has not been fully demonstrated in patients older than age 60.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Histamine is contraindicated in the following cases:

Pregnancy

Pregnancy

Lactation

Lactation

Significantly compromised cardiac function

at least one of
New York Heart Classification finding
New York Heart Association Classification - Class IV

Steroids, clonidine, H₂ blocking agents

at least one of
Corticosteroid drugs
Clonidine
H2-receptor antagonists
Anabolic steroids

Patients who have received an allogenic stem cell transplant

Allogeneic peripheral blood stem cell transplant

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