Hydrochlorothiazide

Chemical formula: C₇H₈ClN₃O₄S₂  Molecular mass: 297.739 g/mol  PubChem compound: 3639

Therapeutic indications

Hydrochlorothiazide is indicated for:

Edema of heart failure

Population group: only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

Cardiac edema

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Edema of nephrotic syndrome

Population group: only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

Interstitial edema and additionally Nephrotic syndrome

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Hypertension

Population group: only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

Hypertension

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Diabetes insipidus

Population group: only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

Diabetes insipidus

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Nephrolithiasis due to idiopathic hypercalciuria

Population group: only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

Familial idiopathic hypercalciuria and additionally Kidney stone

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Mild to moderate arterial hypertension

Population group: only adults (18 years old or older)

Hypertension

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Oedema accompanying with premenstrual tension syndrome

Population group: only adults (18 - 65 years old)

Interstitial edema and additionally Premenstrual tension syndrome

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Hydrochlorothiazide is contraindicated in the following cases:

Pregnancy

Pregnancy

Severe hepatic failure

Hepatic failure stage IV

Gout

Gout

Severe renal failure

at least one of

Renal failure stage 5: Kidney failure (GFR <15 mL/min/1.73 m2 or dialysis)

Lithium

Lithium

Anuria

Anuria

Addison's disease

Addison's disease

Pre-existing hypercalcaemia

Hypercalcemia

Basal cell carcinomas and/or squamous cell carcinomas of the skin and lip

at least one of
Basal cell carcinoma of skin
Basal cell carcinoma of skin of lip
Squamous cell carcinoma of skin
Squamous cell carcinoma of lip
History of squamous cell carcinoma of skin

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