Hydromorphone

Chemical formula: C₁₇H₁₉NO₃  Molecular mass: 285.338 g/mol  PubChem compound: 5284570

Active ingredient description

Hydromorphone is an agonist of mu receptors. The pharmacological actions of hydromorphone and morphine do not differ significantly. Hydromorphone and related opioids produce their major effects on the central nervous system and bowel. Hydromorphone is indicated for the relief of severe pain in cancer.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
N02AA03 Hydromorphone N Nervous system → N02 Analgesics → N02A Opioids → N02AA Natural opium alkaloids
Discover more medicines within N02AA03

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
PALLADONE Prolonged release capsule Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
PALLADONE Solution for injection or infusion Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
DILAUDID Solution for injection FDA, National Drug Code (US) MPI, US: SPL/PLR

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 466-99-9
DrugBank Drug: DB00327
PubChem Compound: 5284570
RxNorm Ingredient: 3423
SNOMED-CT Concept: 44508008
Hydromorphone (substance)
UNII Identifier: Q812464R06
HYDROMORPHONE

Medicines

Hydromorphone is an active ingredient of these brands:

United States (US)

  • DILAUDID as HYDROMORPHONE HYDROCHLORIDE
  • EXALGO as HYDROMORPHONE HYDROCHLORIDE

Australia (AU)

  • DILAUDID as HYDROMORPHONE HYDROCHLORIDE
  • JURNISTA as HYDROMORPHONE HYDROCHLORIDE

Austria (AT)

  • HYDAGELAN as HYDROMORPHONE HYDROCHLORIDE
  • HYDAL as HYDROMORPHONE HYDROCHLORIDE

Canada (CA)

  • DILAUDID as HYDROMORPHONE HYDROCHLORIDE

Estonia (EE)

  • JURNISTA as HYDROMORPHONE HYDROCHLORIDE

Finland (FI)

  • HYDOFON as HYDROMORPHONE HYDROCHLORIDE
  • PALLADON as HYDROMORPHONE HYDROCHLORIDE

France (FR)

Germany (DE)

Ireland (IE)

Japan (JP)

  • NARURAPID as HYDROMORPHONE HYDROCHLORIDE
  • NARUSUS as HYDROMORPHONE HYDROCHLORIDE
  • NARUVEIN as HYDROMORPHONE HYDROCHLORIDE

Netherlands (NL)

  • PALLADON as HYDROMORPHONE HYDROCHLORIDE

Singapore (SG)

  • JURNISTA as HYDROMORPHONE HYDROCHLORIDE

South Africa (ZA)

  • JURNISTA as HYDROMORPHONE HYDROCHLORIDE

Spain (ES)

  • EDUNIX as HYDROMORPHONE HYDROCHLORIDE
  • JURNISTA as HYDROMORPHONE HYDROCHLORIDE

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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