Chemical formula: Mg₆Al₂(CO₃)(OH)₁₆ * 4H₂O Molecular mass: 619.973 g/mol
Hydrotalcite interacts in the following cases:
Hydrotalcite may affect the absorption of certain drugs, e.g. tetracyclines, quinolones such as ciprofloxacin, ofloxacin, formulations containing iron, digoxin. Therefore, a period of 1 to 2 hours should be allowed between the administration of hydrotalcite and other medicines.
Hydrotalcite may affect the absorption of certain drugs, e.g. chenodeoxycholic acid, cimetidine, coumarin derivatives, anticholinergics, isoniazid, carbenoxolone, phenobarbital. Therefore, a period of 1 to 2 hours should be allowed between the administration of hydrotalcite and other medicines.
Long-term treatment and high dose administration should be avoided in patients with Alzheimer’s disease or other forms of dementia.
Hydrotalcite should not be taken with acidic foods / drinks (fruit juices, wine, etc.), because it increases the absorption of aluminum hydroxide from the intestine.
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