Hyoscyamine

Chemical formula: C₁₇H₂₃NO₃  Molecular mass: 289.369 g/mol  PubChem compound: 154417

Active ingredient description

Hyoscyamine inhibits specifically the actions of acetylcholine on structures innervated by postganglionic cholinergic nerves and on smooth muscles that respond to acetylcholine but lack cholinergic innervation. Hyoscyamine inhibits gastrointestinal propulsive motility and decreases gastric acid secretion. It also controls excessive pharyngeal, tracheal and bronchial secretions.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
A03BA03 Hyoscyamine A Alimentary tract and metabolism → A03 Drugs for functional gastrointestinal disorders → A03B BELLADONNA AND DERIVATIVES, PLAIN → A03BA Belladonna alkaloids, tertiary amines
Discover more medicines within A03BA03

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
HYOSCYAMINE SULFATE Extended-release tablet FDA, National Drug Code (US) MPI, US: SPL/Old
HYOSCYAMINE SULFATE Solution for injection FDA, National Drug Code (US) MPI, US: SPL/Old

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 101-31-5
DrugBank Drug: DB00424
KEGG Drug: D00147
PubChem Compound: 154417
RxNorm Ingredient: 153970
SNOMED-CT Concept: 372757002
Hyoscyamine (substance)
UNII Identifier: PX44XO846X
HYOSCYAMINE

Medicines

Hyoscyamine is an active ingredient of these brands:

Brazil (BR)

  • (combination) TROPINAL as HYOSCYAMINE HYDROBROMIDE

Hong Kong (HK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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