Chemical formula: C₂₄H₂₇FN₂O₄ Molecular mass: 426.481 g/mol PubChem compound: 71360
The mechanism of action of iloperidone in schizophrenia and bipolar I disorder is unknown. However, the efficacy of iloperidone could be mediated through a combination of dopamine type 2 (D2) and serotonin type 2 (5-HT2) antagonism. Iloperidone forms an active metabolite, P88, that has an in vitro receptor binding profile similar to the parent drug.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| N05AX14 | Iloperidone | N Nervous system → N05 Psycholeptics → N05A Antipsychotics → N05AX Other antipsychotics |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| FANAPT Tablet | FDA, National Drug Code (US) | MPI, US: SPL/PLR |
Iloperidone is an active ingredient of these brands:
United States (US)Israel (IL)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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