Indometacin Other names: Indomethacin

Chemical formula: C₁₉H₁₆ClNO₄  Molecular mass: 357.788 g/mol  PubChem compound: 3715

Therapeutic indications

Indometacin is indicated for:

Rheumatoid arthritis

Population group: only adults (18 years old or older)

Rheumatoid arthritis

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Dysmenorrhea

Population group: women, only adults (18 - 65 years old)

Period pain

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Acute gouty arthritis

Population group: only adults (18 years old or older)

Acute gout

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Osteoarthritis

Population group: only adults (18 years old or older)

Osteoarthritis

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Ankylosing spondylitis

Population group: only adults (18 years old or older)

Ankylosing spondylitis

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Degenerative joint disease of the hip

Population group: only adults (18 years old or older)

OA - Osteoarthritis of hip

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Low back pain

Population group: only adults (18 years old or older)

Low back pain

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Inflammation, pain, oedema following orthopaedic procedures

Population group: only adults (18 years old or older)

Postoperative pain and additionally Operation on musculoskeletal system

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Indometacin is contraindicated in the following cases:

History of peptic ulcer or active peptic ulcer

at least one of
Peptic ulcer
H/O: peptic ulcer

Pregnancy

Pregnancy

Lactation

Lactation

Nasal polyps associated with angioneurotic oedema as a result of therapy with non-steroidal anti-inflammatory drugs

Polyp of nasal cavity and additionally NSAID-induced angio-oedema-urticaria

Severe cardiac failure

Heart failure New York Heart Assosiation Class IV

Severe hepatic failure

Hepatic failure stage IV

Severe renal failure

at least one of

Renal failure stage 5: Kidney failure (GFR <15 mL/min/1.73 m2 or dialysis)

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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Related medicines

Summary of Product Characteristics (SPC) 2018: INDOCID Capsules
Summary of Product Characteristics (SPC) 2018: INDOCID Suppositories
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