Isoprenaline Other names: N-Isopropylnorepinephrine N-Isopropylnoradrenaline L-Isopropylnoradrenaline Isoproterenol Isopropylnorepinephrine Isopropylnoradrenaline Isopropylarterenol Isopropyladrenaline Isopropydrin Isoprenaline Epinephrine Isopropyl Homolog

Chemical formula: C₁₁H₁₇NO₃  Molecular mass: 211.258 g/mol  PubChem compound: 3779

Therapeutic indications

Isoprenaline is indicated for:

Bronchospasm occurring during anaesthesia

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

Bronchospasm and additionally Maintenance of general anaesthesia

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Stokes-Adams attack

Population group: only adults (18 years old or older)

Serious episodes of Adams-Stokes attacks (except when caused by ventricular tachycardia of fibrillation).

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Cardiac arrest

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

Use in cardiac arrest until electric shock or pacemaker therapy, the treatments of choice, are available.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Heart block

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

Mild or transient episodes of heart block that do not require electric shock or pacemaker therapy.

Serious episodes of heart block (except when caused by ventricular tachycardia of fibrillation).

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Fluid and electrolyte replacement therapy

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

As an adjunct to fluid and electrolyte replacement therapy and the use of other medicines and procedures in the treatment of hypovolaemic and septic shock, low cardiac output (hypoperfusion) states, congestive heart failure, and cardiogenic shock.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Isoprenaline is contraindicated in the following cases:

Tachyarrhythmias

Tachyarrhythmia

Tachycardia or heart block caused by digitalis intoxication

at least one of
Tachycardia
Heart block
Allergy to Digitalis glycoside

Ventricular arrhythmias which require inotropic therapy

Ventricular arrhythmia

Recent myocardial infarction

Myocardial infarction

Angina pectoris

Angina

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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