Isosorbide mononitrate

Chemical formula: C₆H₉NO₆  Molecular mass: 191.139 g/mol  PubChem compound: 27661

Therapeutic indications

Isosorbide mononitrate is indicated for:

Prophylaxis of angina pectoris

Population group: only adults (18 years old or older)

For the prophylaxis of angina pectoris.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Congestive heart failure

Population group: only adults (18 years old or older)

As adjunctive therapy in congestive heart failure not responding to cardiac glycosides or diuretics.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Isosorbide mononitrate is contraindicated in the following cases:

Acute myocardial infarction with low filling pressures

Acute myocardial infarction and additionally Low systolic arterial pressure

Acute circulatory failure

Shock

Very low blood pressure

Hypotension

Hypertrophic obstructive cardiomyopathy (HOCM)

Hypertrophic obstructive cardiomyopathy

Constrictive pericarditis

Constrictive pericarditis

Cardiac tamponade

Cardiac tamponade

Aortic valve stenosis

Aortic valve stenosis

Mitral valve stenosis

Mitral valve stenosis

Raised intracranial pressure

Raised intracranial pressure

Anemia

Anemia

Angle-closure glaucoma

Angle-closure glaucoma

Hypovolemia

Hypovolemia

Phosphodiesterase type-5 inhibitors

PDE5 selective inhibitors

Riociguat

Riociguat

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