Itopride

Chemical formula: C₂₀H₂₆N₂O₄  Molecular mass: 358.431 g/mol  PubChem compound: 3792

Active ingredient description

Itopride activates the gastrointestinal propulsive motility by dopamine D2 receptors antagonistic action and acetylcholine esterase inhibitory action. Itopride activates acetylcholine release and inhibits its degradation.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
A03FA07 A Alimentary tract and metabolism → A03 Drugs for functional gastrointestinal disorders → A03F Propulsives → A03FA Propulsives
Discover more medicines within A03FA07

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
PROGIT Film-coated tablet MPI, EU: SmPC
TOPRISAN Film-coated tablet Medicines Authority (MT) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 122898-67-3
DrugBank Drug: DB04924
PubChem Compound: 3792
UNII Identifier: 81BMQ80QRL
ITOPRIDE

Medicines

Itopride is an active ingredient of these brands:

Croatia (HR)

  • ITONORM as ITOPRIDE HYDROCHLORIDE

Cyprus (CY)

Ecuador (EC)

  • PRIDOT as ITOPRIDE HYDROCHLORIDE

Estonia (EE)

Japan (JP)

  • GANATON as ITOPRIDE HYDROCHLORIDE

Lithuania (LT)

  • ASTIPAL as ITOPRIDE HYDROCHLORIDE
  • PROGIT as ITOPRIDE HYDROCHLORIDE
  • ZIRID as ITOPRIDE HYDROCHLORIDE

Malta (MT)

Mexico (MX)

  • DAGLA as ITOPRIDE HYDROCHLORIDE

Nigeria (NG)

  • DYNETIC as ITOPRIDE HYDROCHLORIDE

Poland (PL)

  • PROKIT as ITOPRIDE HYDROCHLORIDE
  • ZIRID as ITOPRIDE HYDROCHLORIDE

Romania (RO)

  • ASKETON as ITOPRIDE HYDROCHLORIDE

Turkey (TR)

  • ZIRID as ITOPRIDE HYDROCHLORIDE

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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